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B-Apoe KO mice
Strain Name
C57BL/6-Apoetm1Bcgen/Bcgen 
Common Name  B-Apoe KO mice
Background C57BL/6 Catalog number 110168
Aliases

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Project background
Apolipoprotein E (ApoE) is primarily produced by the liver and macrophages in the peripheral tissues, or by astrocytes and microglia in the central nervous system. ApoE transports lipoproteins, fat-soluble vitamins and cholesterol into the lymph systems, and then into the blood, preventing the accumulation of cholesterol-rich particles in the plasma. The function of ApoE protein has been widely studied in cardiovascular disease, lipid metabolism, and Alzheimer’s diseases.

Targeting strategy

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