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B-hGDF15 mice
Strain Name
C57BL/6N-Gdf15tm1(GDF15)Bcgen/Bcgen
Common Name  B-hGDF15 mice
Background C57BL/6N Catalog number  111201
Related Genes 
growth differentiation factor 15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB
NCBI Gene ID
23886

mRNA expression analysis


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Strain specific analysis of GDF15 gene expression in wild-type mice and B-hGDF15 mice by RT-PCR. Mouse Gdf15 mRNA was detectable in kidney of wild-type (+/+). Human GDF15 mRNA was detectable only in H/H but not in +/+ mice.


Protein expression analysis 


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Strain specific GDF15 expression analysis in homozygous B-hGDF15 mice by ELISA. Serum was collected from wild-type mice (+/+) and homozygous B-hGDF15 mice (H/H) analyzed by ELISA with species-specific GDF15 ELISA kit. Mouse GDF15 was exclusively detectable in wild-type mice and human GDF15 was exclusively detectable in homozygous B-hGDF15 mice. ND: Not detected.