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B-hITGB1 mice
Strain Name
C57BL/6-Itgb1tm1(ITGB1)Bcgen/Bcgen
Common Name  B-hITGB1 mice
Background C57BL/6 Catalog number  110901
Related Genes 
integrin subunit beta 1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB
NCBI Gene ID
16412

mRNA expression analysis


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Strain specific analysis of ITGB1 gene expression in wild-type mice and B-hITGB7 mice by RT-PCR. 
Mouse Itgb1 mRNA was detectable in splenocytes of wild-type mice (+/+). Human ITGB1 mRNA was detectable only in homozygous B-hITGB7 but not in wild-type mice.

Protein expression analysis 


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Strain specific ITGB1 expression analysis in homozygous B-hITGB1 mice by flow cytometry. 

Splenocytes were collected from wild-type mice (+/+) and homozygous B-hITGB1 mice (H/H) analyzed by flow cytometry with species-specific anti-ITGB1 antibody. Mouse ITGB1 was detectable in WT mice. Human ITGB1 were exclusively detectable in homozygous B-hITGB1 mice (H/H).