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With the improvement of living standards and medical technology, human life expectancy is gradually increasing, which has led to an unprecedented increase in the global elderly population. As a result, the burden of age-related diseases has also increased exponentially. Thus, it is necessary to improve understanding of aging and disease processes at the biological, organ and cellular levels, to develop therapeutic strategies for the prevention and treatment of aging-related diseases based on aging-related molecular pathways.
Since mice are easy to raise and handle, and have a shorter life span (~2.5 years), they are an attractive mammalian model organism for research on aging and related diseases. Because C57BL/6J is one of the most widely used inbred strains, the survival of C57BL/6J mice has been used to estimate comparable human ages. Young adult mice are 3-6 months old (20-30 year old humans), middle-aged mice are 10-15 months old (38-47 year old humans) and elderly mice are 18-24 months old (56-69 year old humans).
Biocytogen provides high-quality aged mice that can be used for research of aging, tumors, metabolic diseases and other related diseases. The currently available strains are as follows: