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B-hCALCRL mice
Strain Name
C57BL/6-Calcrltm1(CALCRL)Bcgen/Bcgen
Common Name   B-hCALCRL mice  
Background C57BL/6 Catalog number  110115
Aliases 
CRLR; CGRPR; LMPHM8
NCBI Gene ID
54598

mRNA and protein expression analysis

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Strain specific analysis of CALCRL gene expression in B-CALCRL mice by RT-PCR and western blot. A. Mouse Calcrl mRNA was detectable in lung of wild-type (+/+) mice. Human CALCRL mRNA was detectable only in homozygous B-hCALCRL mice (H/H) but not in wild-type mice. B. Human CALCRL protein was detectable in lung of homozygous B-hCALCRL mice (H/H) and wild type mice,but not in cerebellum. This anti-human CALCRL antibody cross reacts with mouse Calcrl. Taken together, the results suggest that B-hCALCRL mice successfully express human CALCRL.