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B-hANGPTL4 mice
Strain Name
C57BL/6N-Angptl4tm1(ANGPTL4)Bcgen/Bcgen
Common Name  B-hANGPTL4 mice
Background C57BL/6N Catalog number  111085
Related Genes 
ARP4, FIAF, HARP, HFARP, NL2, PGAR, TGQTL, UNQ171, pp1158 

mRNA expression analysis



Strain specific analysis of ANGPTL4 gene expression in wild-type mice and B-hANGPTL4 mice by RT-PCR. 
Mouse Angptl4 mRNA was detectable in fat of wild-type mice (+/+). Human ANGPTL4 mRNA was detectable in homozygous B-hANGPTL4 mice but not in wild-type mice.


Protein expression analysis 



Strain specific ANGPTL4 expression analysis in homozygous B-hANGPTL4 mice by western blot. 
Fatty tissue was collected from wild-type mice (+/+) and homozygous B-hANGPTL4 mice (H/H), and analyzed by western blot. ANGPTL4 was both detectable in wild-type mice and B-hANGPTL4 mice (H/H) due to the cross-reactivity of antibody. And the levels of ANGPTL4 was higher under fasted state both in wild-type mice and B-hANGPTL4 mice.