B-hCXCL7/hCXCL4 mice_Biocytogen Pharmaceuticals (Beijing) Co., Ltd._Biocytogen, drug development, antibody discovery

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동물/세포 모델

동물/세포모델

Humanized Mouse Models

Cytokine Humanized Mice

Text

B-hCXCL7/hCXCL4 mice

Strain Name	C57BL/6N-Ppbp^{tm1(PPBP)Bcgen} Pf4^{tm1(PF4)Bcgen}/Bcgen	Common Name	B-hCXCL7/hCXCL4 mice
Background	C57BL/6N	Catalog number	112063
Aliases	PPBP (PBP; TC1; TC2; TGB; LDGF; MDGF; TGB1; B-TG1; CTAP3; CXCL7) PF4 (PF-4; CXCL4; SCYB4)

Protein expression analysis

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Strain specific CXCL7 expression analysis in homozygous B-hCXCL7/hCXCL4 mice by ELISA. Serum was collected from wild-type mice (+/+) and homozygous B-hCXCL7/hCXCL4 mice (H/H), and analyzed by ELISA with species-specific CXCL7 ELISA kit. Mouse CXCL7 was detectable in wild-type mice. Human CXCL7 was exclusively detectable in homozygous B-hCXCL7/hCXCL4 mice but not in wild-type mice.

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Strain specific CXCL4 expression analysis in homozygous B-hCXCL7/hCXCL4 mice by ELISA. Serum was collected from wild-type mice (+/+) and homozygous B-hCXCL7/hCXCL4 mice (H/H), and analyzed by ELISA with species-specific CXCL4 ELISA kit. Mouse CXCL4 was detectable in wild-type mice. Human CXCL4 was exclusively detectable in homozygous B-hCXCL7/hCXCL4 mice but not in wild-type mice.