| Strain Name |
C57BL/6-Il10rbtm1(IL10RB)Bcgen/Bcgen
|
Common Name | B-hIL10RB mice |
| Background | C57BL/6 | Catalog number | 110773 |
|
Related Genes |
CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2 | ||
|
NCBI Gene ID |
16155 | ||
mRNA expression analysis
Strain specific analysis of IL10RB gene expression in wild-type mice and B-hIL10RB mice by RT-PCR. Mouse Il10rb mRNA was detectable in kidney of wild-type C57BL/6 mice (+/+). Human IL10RB mRNA was detectable only in homozygous B-hIL10RB mice (H/H), but not in wild-type mice.
Protein expression analysis
Strain specific IL10RB expression analysis in B-hIL10RB mice by flow cytometry. Monocytes from spleen and blood were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hIL10RB mice (H/H), and analyzed by flow cytometry with species-specific anti-IL10RB antibody. Mouse IL10RB was detectable in wild-type mice. Human IL10RB was exclusively detectable in homozygous B-hIL10RB mice but not in wild-type mice.
