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B-hMAG mice
Strain Name
C57BL/6N-Magtm1(MAG)Bcgen/Bcgen 
Common Name  B-hMAG mice
Background C57BL/6N Catalog number 111033
Aliases  MAG (GMA; S-MAG; SPG75; SIGLEC4A; SIGLEC-4A)
mRNA and Protein expression analysis

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Strain specific analysis of MAG gene expression in wild-type mice and B-hMAG mice by RT-PCR. Mouse Mag mRNA was detectable in brain of wild-type mice (+/+). Human MAG mRNA was detectable only in homozygous B-hMAG mice (H/H) but not in wild-type mice.

Strain specific MAG expression analysis in homozygous B-hMAG mice by ELISA. Brain was collected from wild-type mice (+/+) and homozygous B-hMAG mice (H/H), and analyzed by ELISA with species-specific MAG ELISA kit. MAG was detectable in wild-type mice and homozygous B-hMAG mice, as the antibody is crossly reactive with MAG in human and mice.