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B-hSOST mice
Strain Name
C57BL/6-Sosttm1(SOST)Bcgen/Bcgen
Common Name  B-hSOST mice
Background C57BL/6 Catalog number  110111
Related Genes 
SOST (Sclerostin), CDD, DAND61, VBCH
NCBI Gene ID
74499

mRNA expression analysis 


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Strain specific analysis of SOST gene expression in C57BL/6(+/+) and homozygous B-hSOST mice by RT-PCR. 
Mouse Sost mRNA was detectable only in heart and testis of C57BL/6(+/+) mice. Human SOST mRNA was detectable only in homozygous B-hSOST mice, but not in C57BL/6(+/+) mice. 

Protein expression analysis 

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Strain specific analysis of SOST gene expression in C57BL/6(+/+) and homozygous B-hSOST(H/H) mice by western blot. 
Heart were collected from C57BL/6(+/+) and homozygous B-hSOST (H/H) mice. SOST was detectable in the heart of the C57BL/6(+/+) and B-hSOST (H/H) mice due to the cross-reactivity of antibodies.