B-hCD22 mice
| Strain Name |
C57BL/6-Cd22tm1(CD22)Bcgen/Bcgen
|
Common Name | B-hCD22 mice |
| Background | C57BL/6 | Catalog number |
110775 |
|
Related Genes |
cluster of differentiation-22, SIGLEC2 | ||
|
NCBI Gene ID |
12483 | ||
mRNA expression analysis
Strain specific analysis of CD22 gene expression in WT and homozygous B-hCD22 mice by RT-PCR. Mouse Cd22 mRNA was detectable in splenocytes of wild-type (+/+) mice. Human CD22 mRNA was detectable only in H/H, but not in +/+ mice.
protein expression analysis
Strain specific CD22 expression analysis in homozygouse B-hCD22 mice by flow cytometry. Splenocytes were collected from WT and homozygous B-hCD22 (H/H) mice, and analyzed by flow cytometry with species-specific CD22 antibody. Mouse CD22 was detectable in WT mice. Human CD22 was exclusively detectable in homozygous B-hCD22 but not WT mice.
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