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B-hIL10RB mice
Strain Name
C57BL/6-Il10rbtm1(IL10RB)Bcgen/Bcgen 
Common Name  B-hIL10RB mice
Background C57BL/6 Catalog number  110773
Related Genes 
CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2
NCBI Gene ID
16155

mRNA expression analysis


Strain specific analysis of IL10RB gene expression in wild-type mice and B-hIL10RB mice by RT-PCR. Mouse Il10rb mRNA was detectable in kidney of wild-type C57BL/6 mice (+/+). Human IL10RB mRNA was detectable only in homozygous B-hIL10RB mice (H/H), but not in wild-type mice.




Protein expression analysis



Strain specific IL10RB expression analysis in B-hIL10RB mice by flow cytometry. Monocytes from spleen and blood were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hIL10RB mice (H/H), and analyzed by flow cytometry with species-specific anti-IL10RB antibody. Mouse IL10RB was detectable in wild-type mice. Human IL10RB was exclusively detectable in homozygous B-hIL10RB mice but not in wild-type mice.