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B-hNOTCH1 mice
Strain Name C57BL/6-Notch1tm1(NOCTH1)Bcgen/Bcgen  Common Name  B-hNOTCH1 mice
Background C57BL/6 Catalog number 110904
Aliases

hN1, AOS5, TAN1, AOVD1, ICN1

Protein expression analysis in thymus

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Strain specific NOTCH1 expression analysis in homozygous B-hNOTCH1 mice by flow cytometry. Thymus were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hNOTCH1 mice (H/H), and analyzed by flow cytometry with species-specific anti-NOTCH1 antibody. Mouse NOTCH1 was detectable in wild-type mice. Human NOTCH1 was exclusively detectable in homozygous B-hNOTCH1 mice.

Protein expression analysis in lung

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Strain specific NOTCH1 expression analysis in homozygous B-hNOTCH1 mice by flow cytometry. Lung were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hNOTCH1 mice (H/H), and analyzed by flow cytometry with species-specific anti-NOTCH1 antibody. Mouse NOTCH1 was not detectable in wild-type mice. Human NOTCH1 was not detectable in homozygous B-hNOTCH1 mice.

Protein expression analysis in kidney

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Strain specific NOTCH1 expression analysis in homozygous B-hNOTCH1 mice by flow cytometry. Kidney were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hNOTCH1 mice (H/H), and analyzed by flow cytometry with species-specific anti-NOTCH1 antibody. Mouse NOTCH1 was not detectable in wild-type mice. Human NOTCH1 was not detectable in homozygous B-hNOTCH1 mice.