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B-hPD-1/hBTLA mice
Strain Name
C57BL/6-Pdcd1tm1(PDCD1)Bcgen Btlatm1(BTLA)Bcgen/Bcgen
Common Name  B-hPD-1/hBTLA mice
Background C57BL/6 Catalog number  120517
Related Genes 
PD-1 (Programmed death-1) ;
BTLA 
(B and T lymphocyte associated)
NCBI Gene ID
18566208154

mRNA expression analysis 


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Protein Expression Analysis



Splenocytes from both wild type (WT) C57BL/6 and homozygous B-hPD-1/hBTLA mice were analyzed by flow cytometry. Mouse BTLA+ B cells were detectable in the WT C57BL/6 mice, while human BTLA+ B cells were detectable in the homozygous B-hPD-1/hBTLA mice.



Splenocytes from both wild type (WT) C57BL/6 and homozygous B-hPD-1/hBTLA mice were by flow cytometry. Mouse PD-1+ T cells were detectable in the WT C57BL/6 mice, while human PD-1+ T cells were detectable in the homozygous B-hPD-1/hBTLA mice.