B-hPD-1/hPD-L1/hLAG3 plus/hVSIG4 mice_Biocytogen Pharmaceuticals (Beijing) Co., Ltd._Biocytogen, drug development, antibody discovery

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동물/세포 모델

동물/세포모델

Humanized Mouse Models

Humanizad Mouse Models

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B-hPD-1/hPD-L1/hLAG3 plus/hVSIG4 mice

Strain Name	C57BL/6-Pdcd1^{tm1(PDCD1)Bcgen} Cd274^{tm1(CD274)Bcgen} Lag3^{tm3(LAG3)Bcgen} Vsig4^{tm3(VSIG4)Bcgen}/Bcgen	Common Name	B-hPD-1/hPD-L1/hLAG3 plus/hVSIG4 mice
Background	C57BL/6	Catalog number	113107
Related Genes	PDCD1: CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1 CD274: B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, hPD-L1 LAG3: CD223 VSIG4: CRIg, Z39IG
NCBI Gene ID	18566,60533,16768,278180

B-hPD-1/hPD-L1/hLAG3 plus/hVSIG4 mice were derived from mating B-hPD-1/hPD-L1/hLAG3 plus mice (130572)and B-hVSIG4 mice (111035) together. For validation data of this mouse model, you can refer to the validation data from the related gene humanized mouse models.