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B-hTIGIT mice(C)
Strain Name BALB/cCrSlcNifdc-Tigittm1(TIGIT)Bcgen/Bcgen  Common Name  B-hTIGIT mice(C) 
Background BALB/cCrSlcNifdc Catalog number 112252
Aliases 
VSIG9, VSTM3, WUCAM
Protein expression analysis

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Strain specific TIGIT expression analysis in homozygous B-hTIGIT mice(C) by flow cytometry. Splenocytes were collected from wild-type BALB/c mice (+/+) and homozygous B-hTIGIT mice(C) (H/H) stimulated with anti-CD3ε in vivo, and analyzed by flow cytometry with species-specific anti-TIGIT antibody. Mouse TIGIT was detectable on CD4+ T cells and CD8+ T cells of wild-type mice. Human TIGIT was exclusively detectable on CD4+ T cells and CD8+ T cells of homozygous B-hTIGIT mice(C) but not in wild-type mice.

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Strain specific TIGIT expression analysis in homozygous B-hTIGIT mice(C) by flow cytometry. Splenocytes were collected from wild-type BALB/c mice (+/+) and homozygous B-hTIGIT mice(C) (H/H) stimulated with anti-CD3ε in vivo, and analyzed by flow cytometry with species-specific anti-TIGIT antibody. Mouse TIGIT was detectable on Tregs and NK cells of wild-type mice. Human TIGIT was exclusively detectable on Treg cells and NK cells of homozygous B-hTIGIT mice(C) but not in wild-type mice.