Strain specific analysis of CD63 gene expression in wild type (WT) and B-hCD63 mice by RT-PCR. 

Mouse Cd63 mRNA was detectable only in kidney of wild type (+/+) mice. Human CD63 mRNA was detectable only in H/H but not in +/+ mice. 

Strain specific CD63 expression analysis in homozygous B-hCD63 mice by flow cytometry. 

Macrophages were collected from bone marrow of WT and homozygous B-hCD63 mice, and analyzed by flow cytometry with species-specific CD63 antibody. Mouse CD63 was detectable in WT mice. Human CD63 was exclusively detectable in homozygous B-hCD63 mice but not WT mice.

Strain specific CD63 expression analysis in homozygous B-hCD63 mice by flow cytometry. 

Monocytes were collected from bone marrow of WT and homozygous B-hCD63 mice, and analyzed by flow cytometry with species-specific CD63 antibody. Mouse CD63 was detectable in WT mice. Human CD63 was exclusively detectable in homozygous B-hCD63 mice but not WT mice.