Strain Name
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C57BL/6N-Dll3tm1(DLL3)Bcgen/Bcgen
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Common Name
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B-hDLL3 mice
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Background
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C57BL/6N
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Catalog number
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110926
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Aliases
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DLL3, SCDO1, delta like canonical Notch ligand 3
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mRNA expression analysis
Strain specific analysis of DLL3 gene expression in wild type (WT) mice and B-hDLL3 mice by RT-PCR. Mouse Dll3 mRNA was detectable in testis of WT mice (+/+). Human DLL3 mRNA was detectable in homozygous B-hDLL3 mice (H/H) but not in WT mice (+/+).
Protein expression analysis
Strain specific DLL3 expression analysis in homozygous B-hDLL3 mice by western blot. Testis and lung were collected from wild type (WT) mice (+/+) and homozygous B-hDLL3 mice (H/H), and analyzed by western blot with anti-DLL3 antibody. DLL3 was detectable in WT mice (+/+) and homozygous B-hDLL3 mice (H/H) due to the cross-reactivity of antibodies.