Strain Name
|
C57BL/6N-Gpc1tm1(GPC1)/Bcgen
|
Common Name
|
B-hGPC1 mice
|
Background
|
C57BL/6N
|
Catalog number
|
111239
|
Aliases
|
GPC1, glypican, glypican 1
|
mRNA expression analysis
Strain specific analysis of GPC1 gene expression in wild type (WT) mice and B-hGPC1 mice by RT-PCR. Mouse Gpc1 mRNA was detectable only in lung of WT mice (+/+). Human GPC1 mRNA was detectable only in homozygous B-hGPC1 mice (H/H) but not in WT mice (+/+).
Protein expression analysis
Strain specific GPC1 expression analysis in homozygous B-hGPC1 mice by western blot. Heart was collected from wild type (WT) mice (+/+) and homozygous B-hGPC1 mice (H/H), and analyzed by western blot with anti-GPC1 antibody. Human GPC1 was detectable in homozygous B-hGPC1 mice (H/H).