Strain Name
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C57BL/6N-Nectin4tm2(NECTIN4)Bcgen/Bcgen
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Common Name
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B-hNECTIN4 mice
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Background
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C57BL/6N
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Catalog number
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111702
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Aliases
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LNIR; PRR4; EDSS1; PVRL4; nectin-4
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mRNA expression analysis
Strain specific analysis of NECTIN4 gene expression in wild-type mice and B-hNECTIN4 mice by RT-PCR. Mouse NECTIN4 mRNA was detectable in lung of wild-type mice (+/+). Human NECTIN4 mRNA was detectable only in homozygous B-hNECTIN4 mice (H/H) but not in wild-type mice.
Protein expression analysis
Strain specific NECTIN4 protein expression analysis in wild-type mice and B-hNECTIN4 mice by western blotting. Human NECTIN4 was only detectable in lung and stomach of homozygous B-hNECTIN4 mice but not in wild type mice for species-specific antibody.