Strain Name
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C57BL/6-Ror1tm1(ROR1)Bcgen/Bcgen
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Common Name
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B-hROR1 mice
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Background
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C57BL/6
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Catalog number
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111546
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Aliases
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ROR1 (NTRKR1; dJ537F10.1)
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mRNA expression analysis
Strain specific analysis of ROR1 gene expression in wild-type C57BL/6 mice and B-hROR1 mice by RT-PCR. ROR1 mRNA was detectable in lung of wild-type C57BL/6 mice and homozygous B-hROR1 mice (H/H) due to the high genetic similarity, and we sequenced and confirmed that the extracellular region of homozygous B-hROR1 mice (H/H) is the human ROR1 sequence.
Protein expression analysis
Strain specific ROR1 expression analysis in homozygous B-hROR1 mice by western blot. Tissues were collected from WT mice (+/+) and homozygous B-hROR1 (H/H) mice, and analyzed by western blot with anti-ROR1 antibody. ROR1 was detectable in embryo of WT mice (+/+) and homozygous B-hROR1 mice (H/H) due to the cross-reactivity of antibodies.