Strain Name |
C57BL/6N-Fabp4tm1(icre)Bcgen/Bcgen
|
Stock No. |
110152 |
Common name |
B-Fabp4-iCre mice |
Gene symbol and name |
fatty acid binding protein 4 |
Strain of origin |
C57BL/6N |
Chromosome | 2 |
Coat color |
Black |
Dietary information | Growth and reproduction diet for experimental mice |
|
|
Phenotype Analysis
Scheme for generating RhebAD KO mice. The RhebFL/FL mice were crossed with Fabp4-Cre mice (Fabp4-Cre mice were purchased from Biocytogen Co.Ltd., Beijing, China) to obtain RhebAD KO mice. Rheb was not detected in the interscapular BAT, inguinal and epididymal WAT of RhebAD KO mice. Compared to control mice, the interscapular BAT pads of RhebAD KO mice were significantly lighter and smaller, while no significant differences were observed in the inguinal and epididymal WAT.
Instructions of genomic DNA extraction
chematic representation of the toe clipping.
Gene editing strategy