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2025
AACR 2025: Bispecific antibody drug conjugates (bsADCs) targeting DLL3 and B7-H3 demonstrated potent anti-tumor activity in preclinical models of small cell lung cancer (SCLC)
2025
AACR 2025: BCG033: a first-in-class PTK7×TROP2 bispecific ADC demonstrating potent and broad efficacy in various preclinical models
2025
AACR 2025: A novel PD-1, IL12Rβ1 and IL12Rβ2 humanized mouse model for evaluating the combined efficacy of anti-tumor therapies
2025
AACR 2025: A novel IL12Rβ1 and IL12Rβ2 humanized mouse model for preclinical toxicity evaluation of human IL-12 analogs
2025
AACR 2025: YH006: a next-generation CTLA-4×OX40 Treg antagonist, demonstrates superior tumor-infiltrating Treg-depletion efficacy and favorable manufacturability
2025
AACR 2025: Humanized GDF15 model for simulating weight loss induced by GDF15 secretion in tumors
2025
AACR 2025: Animal models for evaluating the efficacy of anti-human HER2 ADC alone or in combination with IO therapy
2025
AACR 2025: Development of TNFR2, TNFR1 and LTBR humanized mouse model for evaluating anti-human LTBR antibodies
2025
AACR 2025: Preclinical evaluation of CD3/DLL3 bispecific antibody in syngeneic and humanized mouse models for solid tumor treatment
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