B-hCCL20 mice_Biocytogen Pharmaceuticals (Beijing) Co., Ltd._Biocytogen, drug development, antibody discovery

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동물/세포 모델

동물/세포모델

Humanized Mouse Models

GPCR Humanized Mice

Text

B-hCCL20 mice

Strain Name	C57BL/6N-Ccl20^{tm1(CCL20)Bcgen}/Bcgen	Common Name	B-hCCL20 mice
Background	C57BL/6N	Catalog number	110854
Related Genes	CKb4, Exodus, LARC, MIP-3-alpha, MIP-3a, MIP3A, SCYA20, ST38

Protein expression analysis

Strain specific CCL20 expression analysis in homozygous B-hCCL20 mice by ELISA. Thymus grinding supernatant was collected from wild-type mice (+/+) and homozygous B-hCCL20 mice (H/H), and analyzed by ELISA with species-specific CCL20 ELISA kit. Mouse CCL20 was detectable in wild-type mice. Human CCL20 was exclusively detectable in homozygous B-hCCL20 mice but not in wild-type mice.