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B-hCD80 mice
Strain Name

C57BL/6-Cd80tm1(CD80)Bcgen/Bcgen

Common Name  B-hCD80 mice
Background C57BL/6 Catalog number 110935
Related Genes 
B7、BB1、B7-1、B7.1、LAB7、CD28LG、CD28LG1

mRNA expression analysis

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Strain specific analysis of CD80 gene expression in wild type (WT) mice and B-hCD80 mice by RT-PCR. Mouse Cd80 mRNA was detectable only in splenocytes of WT mice (+/+). Human CD80 mRNA was detectable only in homozygous B-hCD80 mice (H/H) but not in WT mice (+/+). 

Protein expression analysis in macrophages


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Strain specific CD80 expression analysis in homozygous B-hCD80 mice by flow cytometry. Peritoneal exudative macrophages (PEMs) were collected from wild type (WT) mice (+/+) and homozygous B-hCD80 mice (H/H), and analyzed by flow cytometry with species-specific anti-CD80 antibody. Mouse CD80 was detectable in WT mice (+/+). Human CD80 was exclusively detectable in homozygous B-hCD80 mice (H/H) but not in WT mice (+/+).

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Strain specific CD80 expression analysis in homozygous B-hCD80 mice by flow cytometry. Splenocytes were collected from wild type (WT) mice (+/+) and homozygous B-hCD80 mice (H/H), and analyzed by flow cytometry with species-specific anti-CD80 antibody. Mouse CD80 was detectable in WT mice (+/+). Human CD80 was exclusively detectable in homozygous B-hCD80 mice (H/H) but not in WT mice (+/+).