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B-hMERTK/hGAS6 mice
Strain Name
C57BL/6-Mertktm2(MERTK)Bcgen Gas6tm1(GAS6)Bcgen/Bcgen  
Common Name  B-hMERTK/hGAS6 mice
Background C57BL/6 Catalog number 112490
Related Genes 
Mertk (Me; Ny; Eyk; Mer; Nyk; nmf1; nmf12);Gas6 (AXSF; AXLLG)

Protein expression analysis


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Strain specific GAS6 expression analysis in homozygous B-hMERTK/hGAS6 mice by ELISA. Plasma was collected from wild-type mice (+/+) and homozygous B-hMERTK/hGAS6 mice (H/H), and analyzed by ELISA with species-specific GAS6 ELISA kit. Mouse GAS6 was detectable only in wild-type mice. Human GAS6 was detectable in homozygous B-hMERTK/hGAS6 mice but not in wild-type mice.

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Strain specific MERTK expression analysis in homozygous B-hMERTK/hGAS6 mice by flow cytometry. Peritoneal washes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hMERTK/hGAS6 mice (H/H). Flow cytometry was analyzed with species-specific anti-MERTK antibody. Mouse MERTK was detectable in macrophage of wild-type mice. Human MERTK was only detectable in macrophage of homozygous B-hMERTK/hGAS6 mice but not in wild-type mice.