B-hEPCAM mice_Biocytogen Pharmaceuticals (Beijing) Co., Ltd._Biocytogen, drug development, antibody discovery

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동물/세포 모델

동물/세포모델

Humanized Mouse Models

Other Humanized Mice

Text

B-hEPCAM mice

Strain Name

C57BL/6-Epcam^{tm1(EPCAM)Bcgen}/Bcgen

Common Name

B-hEPCAM mice

Background

C57BL/6

Catalog number

110826

Aliases

EPCAM (Ber-Ep4, BerEp4, DIAR5, EGP-2, EGP314, EGP40, ESA,

HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, MOC-31, TACSTD1, TROP1)

Protein expression analysis

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Strain specific EPCAM expression analysis in homozygous B-hEPCAM mice by flow cytometry. Lung, small intestine and pancreas were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hEPCAM mice (H/H), and CD45- cells were analyzed by flow cytometry with species-specific anti-EPCAM antibody. Mouse EPCAM was detectable in wild-type mice. Human EPCAM was exclusively detectable in homozygous B-hEPCAM (H/H) but not in wild-type mice.