B-hCD23 mice_Biocytogen Pharmaceuticals (Beijing) Co., Ltd._Biocytogen, drug development, antibody discovery

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동물/세포 모델

동물/세포모델

Humanized Mouse Models

Humanizad Mouse Models

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B-hCD23 mice

Strain Name	C57BL/6N-Fcer2a^{tm1(FCER2)Bcgen}/Bcgen	Common Name	B-hJAM3 mice
Background	C57BL/6N	Catalog number	111091
Aliases	CD23(BLAST-2, CD23, CD23A, CLEC4J, FCE2, FCErII, IGEBF)

Protein expression analysis in spleen and Lymph node

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Strain specific CD23 expression analysis in homozygous B-hCD23 mice by flow cytometry. Spleen and lymph node were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hCD23 mice(H/H), and analyzed by flow cytometry with species-specific anti-CD23 antibody. Mouse CD23 was detectable in wild-type mice. Human CD23 was exclusively detectable in homozygous B-hCD23 mice but not in wild-type mice.