NOD.CB17-PrkdcscidII2rgtm1BcgenAlbtm1(ALB)Bcgen/Bcgen • 111982
Product name | B-NDG hALB mice |
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Catalog number | 111982 |
Strain name | NOD.CB17-PrkdcscidII2rgtm1BcgenAlbtm1(ALB)Bcgen/Bcgen |
Strain background | B-NDG |
NCBI gene ID | 213,3561,5591 (Human) |
Aliases | CD132; CIDX; IL-2RG; IMD4; P64; SCIDX; SCIDX1; DNA-PKC; DNA-PKcs; DNAPK; DNAPKc; DNPK1; HYRC; HYRC1; IMD26; XRCC7; p350; HSA; PRO0883; PRO0903; PRO1341; PRO1341; CD132; SCIDX1; DNA-PKC |
Application | Used for pharmacological or pharmacokinetic studies of drugs that utilize albumin to extend their half-life |
Strain specific ALB expression analysis in homozygous B-NDG hALB mice by ELISA. Serum was collected from B-NDG mice (+/+) and homozygous B-NDG hALB mice (H/H), and analyzed by ELISA with species-specific ALB ELISA kit. Mouse ALB was detectable in B-NDG mice (A). Human ALB was exclusively detectable in homozygous B-NDG hALB mice but not in B-NDG mice (B). In addition, human plasma was collected and assayed for human ALB expression levels as a reference (C).