B-hNCR2 mice

C57BL/6-Igs2tm1(NCR2)Bcgen/Bcgen • 111872

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B-hNCR2 mice

Catalog Number: 111872
Strain Name: C57BL/6-Igs2tm1(NCR2)Bcgen/Bcgen
Strain Background: C57BL/6
NCBI gene ID: 9436 (Human)
Aliases: LY95; CD336; NKP44; NK-p44; dJ149M18.1
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B-hNCR2 mice

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  • Phenotypic analysis

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      Protein expression analysis in spleen NK cells

      Strain specific NCR2 expression analysis in homozygous B-hNCR2 mice by flow cytometry. Splenocytes were collected from wild-type mice (+/+) and homozygous B-hNCR2 mice (H/H), and then were cultured for 4 days under 50 ng/mL hIL12 and hIL15 stimulation ex vivo. Flow cytometry was performed with anti-human NCR2 antibody to detect NCR2 expression. Human NCR2 was exclusively detectable in NK cells of homozygous B-hNCR2 mice.

      * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hNCR2 mice] (Cat# 111872) was purchased from Biocytogen.