B-hNRP1 mice

C57BL/6-Nrp1tm1(NRP1)Bcgen/Bcgen • 111330

B-hNPR1 mice
B-hNTRK1 mice

B-hNRP1 mice

Product nameB-hNRP1 mice
Catalog number111330
Strain nameC57BL/6-Nrp1tm1(NRP1)Bcgen/Bcgen
Strain backgroundC57BL/6
NCBI gene ID8829 (Human)
AliasesBDCA4, CD304, NP1, NRP, VEGF165R

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  • Phenotypic analysis

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      Protein expression analysis in Treg cells

      Strain specific NRP1 expression analysis in homozygous B-hNRP1 mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hNRP1 mice (H/H), and analyzed by flow cytometry with species-specific anti-NRP1 antibody. Mouse NRP1 was detectable in wild-type mice. Human NRP1 was exclusively detectable in homozygous B-hNRP1 but not in wild-type mice.

      Protein expression analysis in CD4+ T cells

      Strain specific NRP1 expression analysis in homozygous B-hNRP1 mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hNRP1 mice (H/H), and analyzed by flow cytometry with species-specific anti-NRP1 antibody. Mouse NRP1 was detectable in wild-type mice. Human NRP1 was exclusively detectable in homozygous B-hNRP1 but not in wild-type mice.