B-hRETN mice

C57BL/6-Retntm1(RETN)Bcgen/Bcgen • 112361

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B-hRETN mice

Catalog Number: 112361
Strain Name: C57BL/6-Retntm1(RETN)Bcgen/Bcgen
Strain Background: C57BL/6
NCBI gene ID: 56729 (Human)
Aliases: ADSF; RENT; RSTN; XCP1; FIZZ3; RETN1
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견적 요청
B-hRETN mice

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  • Targeting strategy
  • Phenotypic analysis

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      Targeting strategy

      Gene targeting strategy for B-hRETN mice. The exons 1~5 of mouse Retn gene that encodes the full-length protein was replaced by human RETN exons 1~4 in B-hRETN mice.

      Protein expression analysis

      Strain specific resistin expression analysis in homozygous B-hRETN mice by ELISA. Serum were collected from wild-type mice C57BL/6 mice (+/+) and homozygous B-hRETN mice (H/H), and analyzed by ELISA with species-specific resistin ELISA kit. Mouse resistin was detectable in wild-type mice (A). Human resistin was exclusively detectable in homozygous B-hRETN mice but not in wild-type mice (B).

      * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hRETN mice] (Cat# 112361) was purchased from Biocytogen.