B-hTFPI mice

C57BL/6-Tfpitm1(TFPI)Bcgen/Bcgen • 111232

견적 요청

B-hTFPI mice

Catalog Number: 111232
Strain Name: C57BL/6-Tfpitm1(TFPI)Bcgen/Bcgen
Strain Background: C57BL/6
NCBI gene ID: 7035 (Human)
Aliases: EPI; TFI; LACI; TFPI1
---
라이선스 옵션 제공 가능
견적 요청
B-hTFPI mice

이 페이지에서

  • Targeting strategy
  • Phenotypic analysis

포스터

모두 보기

    출판물

      관련 제품

      모두 보기
      Targeting strategy

      Gene targeting strategy for B-hTFPI mice. The exons 3-9 of mouse Tfpi gene that encode the full-length protein were replaced by human TFPI exons 2-8 in B-hTFPI mice.

      Protein expression analysis

      Strain specific TFPI expression analysis in wild type (WT) mice and B-hTFPI mice by ELISA. Plasma were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hTFPI mice (H/H), and analyzed by ELISA with TFPI ELISA kit. Mouse TFPI was exclusively detectable in wild-type mice. TFPI was detectable in homozygous B-hTFPI mice (H/H) and wild-type mice (+/+) due to the cross-reactivity of antibodies. ND: not determined.

      * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hTFPI mice] (Cat# 111232) was purchased from Biocytogen.