B-NDG hALB mice

NOD.CB17-PrkdcscidII2rgtm1BcgenAlbtm1(ALB)Bcgen/Bcgen • 111982

B-NDG hairless mice
B-NDG hALB/hFcRn mice

B-NDG hALB mice

Product nameB-NDG hALB mice
Catalog number111982
Strain nameNOD.CB17-PrkdcscidII2rgtm1BcgenAlbtm1(ALB)Bcgen/Bcgen
Strain backgroundB-NDG
NCBI gene ID213,3561,5591 (Human)
AliasesHSA, PRO0883, PRO0903, PRO1341; CD132, CIDX, IL-2RG, IMD4, P64, SCIDX, SCIDX1; DNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, IMD26, XRCC7, p350
ApplicationUsed for pharmacological or pharmacokinetic studies of drugs that utilize albumin to extend their half-life

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  • Phenotypic analysis

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      Protein expression analysis

      Strain specific ALB expression analysis in homozygous B-NDG hALB mice by ELISA. Serum was collected from B-NDG mice (+/+) and homozygous B-NDG hALB mice (H/H), and analyzed by ELISA with species-specific ALB ELISA kit. Mouse ALB was detectable in B-NDG mice (A). Human ALB was exclusively detectable in homozygous B-NDG hALB mice but not in B-NDG mice (B). In addition, human plasma was collected and assayed for human ALB expression levels as a reference (C).