B-hANGPTL4 mice

C57BL/6N-Angptl4tm1(ANGPTL4)Bcgen/Bcgen • 111085

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B-hANGPTL4 mice

Catalog Number: 111085
Strain Name: C57BL/6N-Angptl4tm1(ANGPTL4)Bcgen/Bcgen
Strain Background: C57BL/6N
NCBI gene ID: 51129 (Human)
Aliases: ARP4, FIAF, HARP, HFARP, NL2, PGAR, TGQTL, UNQ171, pp1158
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B-hANGPTL4 mice

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  • Phenotypic analysis

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      mRNA expression analysis
      Strain specific analysis of ANGPTL4 gene expression in wild-type mice and B-hANGPTL4 mice by RT-PCR. Mouse Angptl4 mRNA was detectable in fat of wild-type mice (+/+). Human ANGPTL4 mRNA was detectable in homozygous B-hANGPTL4 mice but not in wild-type mice.
      Protein expression analysis
      Strain specific ANGPTL4 expression analysis in homozygous B-hANGPTL4 mice by western blot. Fatty tissue was collected from wild-type mice (+/+) and homozygous B-hANGPTL4 mice (H/H), and analyzed by western blot. ANGPTL4 was both detectable in wild-type mice and B-hANGPTL4 mice (H/H) due to the cross-reactivity of antibody. And the levels of ANGPTL4 was higher under fasted state both in wild-type mice and B-hANGPTL4 mice.
      * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hANGPTL4 mice] (Cat# 111085) was purchased from Biocytogen.