B-hANGPTL8 mice

C57BL/6N-Angptl8tm1(ANGPTL8)Bcgen/Bcgen • 111230

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B-hANGPTL4 mice plus
B-hANPEP mice

B-hANGPTL8 mice

Product nameB-hANGPTL8 mice
Catalog number111230
Strain nameC57BL/6N-Angptl8tm1(ANGPTL8)Bcgen/Bcgen
Strain backgroundC57BL/6N
NCBI gene ID55908 (Human)
AliasesC19orf80, PRO1185, PVPA599, RIFL, TD26
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  • Phenotypic analysis

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      mRNA expression analysis

      Strain specific analysis of ANGPTL8 gene expression in wild-type mice and B-hANGPTL8 mice by RT-PCR. Mouse Angptl8 mRNA was detectable in the wild-type mice (+/+). Human ANGPTL8 mRNA was detectable only in homozygous B-hANGPTL8 mice but not in wild-type mice.

      Protein expression analysis
      Strain specific ANGPTL8 expression analysis in homozygous B-hANGPTL8 mice by ELISA. Plasma was collected from wild-type mice (+/+) and homozygous B-hANGPTL8 mice (H/H), and analyzed by ELISA. ANGPTL8 was both detectable in wild-type mice and B-hANGPTL8 mice (H/H) due to the cross-reactivity of ELISA kit.