B-hCXCL7 mice

C57BL/6N-Cxcl7tm1(CXCL7)Bcgen/Bcgen • 112404

견적 요청

B-hCXCL7 mice

Catalog Number: 112404
Strain Name: C57BL/6N-Cxcl7tm1(CXCL7)Bcgen/Bcgen
Strain Background: C57BL/6N
NCBI gene ID: 5473 (Human)
Aliases: PBP; TC1; TC2; TGB; LDGF; MDGF; TGB1; B-TG1; CTAP3; CXCL7; NAP-2; SCYB7; THBGB; LA-PF4; THBGB1; Beta-TG; CTAPIII; CTAP-III
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견적 요청
B-hCXCL7 mice

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  • Targeting strategy
  • Phenotypic analysis

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      Targeting strategy

      Gene targeting strategy for B-hCXCL7 mice. The exons 1~3 of mouse Cxcl7 gene that encode the full-length protein were replaced by human CXCL7 exons 1~3 in B-hCXCL7 mice.

      Protein expression analysis
      Strain specific CXCL7 expression analysis in homozygous B-hCXCL7 mice by ELISA. Serum were isolated from wild-type C57BL/6 mice (+/+) and homozygous B-hCXCL7 mice (H/H) and analyzed by ELISA with species-specific CXCL7 ELISA kit. Mouse CXCL7 was detectable in wild-type mice (A). Human CXCL7 was exclusively detectable in homozygous B-hCXCL7 mice (B).
      * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hCXCL7 mice] (Cat# 112404) was purchased from Biocytogen.