B-hIL18BP mice

C57BL/6-Il18bptm1(IL18BP)Bcgen/Bcgen • 112360

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B-hIL18 mice
B-hIL19 mice

B-hIL18BP mice

Product nameB-hIL18BP mice
Catalog number112360
Strain nameC57BL/6-Il18bptm1(IL18BP)Bcgen/Bcgen
Strain backgroundC57BL/6
NCBI gene ID10068 (Human)
AliasesFVHa, IL18BP
제품 주문

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  • Targeting strategy
  • Phenotypic analysis
  • Related products

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      Targeting strategy

      Gene targeting strategy for B-hIL18BP mice. The mouse Il18bp gene, which encodes the full-length protein, was replaced with the sequence of the human IL18BP counterpart gene in the B-hIL18BP mice.

      Protein expression analysis
      Strain specific IL18BP expression analysis in homozygous B-hIL18BP mice by ELISA. Serum was collected from wild-type mice (+/+) and homozygous B-hIL18BP mice (H/H) and analyzed by ELISA with species-specific IL18BP ELISA kit. Mouse IL18BP was detectable in wild-type mice. Human IL18BP was exclusively detectable in homozygous B-hIL18BP mice but not in wild-type mice.
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