B-hTNFA/hTNFR2/hTNFR1/hIL6/hIL6R/hALB plus/hFcRn mice
C57BL/6-Tnftm1(TNF)Bcgen Tnfrsf1btm1(TNFRSF1B)Bcgen Tnfrsf1atm1(TNFRSF1A)Bcgen/Il6tm1(IL6)BcgenIl6rtm2(IL6R)BcgenAlbtm2(ALB)BcgenFcgrttm1(FCGRT)Bcgen/Bcgen • 114636
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B-hTNFA/hTNFR2/hTNFR1/hIL6/hIL6R/hALB plus/hFcRn mice

Catalog Number
114636
Strain Name
C57BL/6-Tnftm1(TNF)Bcgen Tnfrsf1btm1(TNFRSF1B)Bcgen Tnfrsf1atm1(TNFRSF1A)Bcgen/Il6tm1(IL6)BcgenIl6rtm2(IL6R)BcgenAlbtm2(ALB)BcgenFcgrttm1(FCGRT)Bcgen/Bcgen
Strain Background
C57BL/6
NCBI gene ID
7124,7133,7132,3569,3570,213,2217 (Human)
Aliases
DIF; TNFA; IMD127; TNFSF2; TNLG1F; TNF-alpha; p75; TBPII; TNFBR; TNFR2; CD120b; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II; FPF; p55; p60; TBP1; TNF-R; TNFAR; TNFR1; p55-R; CD120a; TNFR55; TNFR60; TNF-R-I; TNF-R55; CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2; IL6Q; gp80; CD126; HIES5; IL-6R; IL6RA; IL6RQ; IL-1Ra; IL-6RA; IL6QTL; IL-6R-1; HSA; FDAHT; PRO0883; PRO0903; PRO1341; FCRN; FcgammaRn; alpha-chain
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      Description

      B-hTNFA/hTNFR2/hTNFR1/hIL6/hIL6R/hALB plus/hFcRn mice were obtain by mating B-hTNFA/hTNFR2/hTNFR1 mice (131706), B-hIL6/hIL6R mice (120557), and B-hALB plus/hFcRn mice (113043). For validation data of this mouse model, you can refer to the validation data from the related gene humanized mouse models.

      * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hTNFA/hTNFR2/hTNFR1/hIL6/hIL6R/hALB plus/hFcRn mice] (Cat# 114636) was purchased from Biocytogen.